Correlates of low hemoglobin A1c in maintenance hemodialysis patients

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A1C and survival in maintenance hemodialysis patients.

OBJECTIVE The optimal target for glycemic control has not been established in diabetic dialysis patients. RESEARCH DESIGN AND METHODS To address this question, the national database of a large dialysis organization (DaVita) was analyzed via time-dependent survival models with repeated measures. RESULTS Of 82,933 patients undergoing maintenance hemodialysis (MHD) in DaVita outpatient clinics...

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Hemoglobin A1c in hemodialysis patients: should one size fit all?

Currently recommended hemoglobin A1c (HbA1c) targets in ESRD patients are identical to those for the general population; an issue of considerable debate. In this issue, Williams and colleagues provide observational data on the association of HbA1c with mortality among nearly 25,000 hemodialysis patients in the United States. Statistically significant findings were observed only among subjects w...

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Low Hemoglobin A1c in Nondiabetic Adults

OBJECTIVE To identify predictors of low hemoglobin A(1c) (HbA(1c)) (<5.0%) and to investigate the association of low HbA(1c) with cause-specific mortality and risk of liver disease hospitalization. RESEARCH DESIGN AND METHODS Prospective cohort study of 13,288 participants in the Atherosclerosis Risk in Communities Study. Logistic regression was used to identify cross-sectional correlates of ...

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Hemoglobin A1c Levels and Mortality in the Diabetic Hemodialysis Population

OBJECTIVE Lowering hemoglobin A(1c) to <7% reduces the risk of microvascular complications of diabetes, but the importance of maintaining this target in diabetes patients with kidney failure is unclear. We evaluated the relationship between A(1c) levels and mortality in an international prospective cohort study of hemodialysis patients. RESEARCH DESIGN AND METHODS Included were 9,201 hemodial...

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Measurement of Hemoglobin A1c

Evaluation of glycemia is used for the diagnosis and management of patients with diabetes. Glucose and hemoglobin A1c (HbA1c) provide complementary information and both are used to assess an individual’s glycemic status. The concentration of glucose in the blood indicates the subject’s glycemia at the time of blood sampling. However, blood glucose concentrations are modified by numerous factors...

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ژورنال

عنوان ژورنال: International Urology and Nephrology

سال: 2012

ISSN: 0301-1623,1573-2584

DOI: 10.1007/s11255-012-0208-y